The Food and Drug Administration warns that acid-reflux drugs Prilosec and Nexium should not be taken with blood-thinner Plavix.
Plavix’s label cautions against the use of the heartburn drugs, as Prilosec and Nexium make the blood-thinning medication half as effective, according to the Los Angeles Times.
Other drugs that should not be taken with Plavix include Tagamet, Intelence, Felbatol, Diflucan, Nizoral, Luvox, Ticlid and Prozac.
The Times reports on a study from Mount Sinai Medical Center in which Prilosec and Protonix were found to be dangerous following balloon angioplasty. In a five-year follow-up, patients taking Prilosec and Protonix were 72 percent and 54 percent more likely to die, respectively, than patients not on heartburn drugs.
A possible alternative to antacids and acid-reducing drugs are digestive enzyme supplements combined with herbal ingredients, including aloe, DGL and marshmallow, which might help soothe an irritated digestive tract.
News of another study confirming the relationship between certain antacids and bone fractures surfaced in mid-2009.
The drugs, proton pump inhibitors and histamine-2 receptor antagonists, increased the risk of hip and thigh fractures, according to HealthDay News. The greatest risk was in people aged 50-59.
Brand names of these drugs include Prilosec, Prevacid, Nexium, Pepcid, Tagamet and Zantac. Researchers have blamed proton pump inhibitors for decreasing the body’s ability to absorb calcium, HealthDay reports.
In this most recent study, people who had hip fractures were 30 percent more likely to be on proton pump inhibitors. Those taking histamine-2 receptor antagonists were at an 18 percent increased fracture risk.
According to the story, people on these drugs are also at an increased risk of contracting food-borne infections.
On a positive note, HealthDay reports that fracture risk decreases when the drugs are discontinued.
Instead of antacids and acid-reducing drugs, a good alternative might be digestive enzyme supplements combined with herbal ingredients such as aloe, DGL and marshmallow.