The Food and Drug Administration warns that acid-reflux drugs Prilosec and Nexium should not be taken with blood-thinner Plavix.
Plavix’s label cautions against the use of the heartburn drugs, as Prilosec and Nexium make the blood-thinning medication half as effective, according to the Los Angeles Times.
Other drugs that should not be taken with Plavix include Tagamet, Intelence, Felbatol, Diflucan, Nizoral, Luvox, Ticlid and Prozac.
The Times reports on a study from Mount Sinai Medical Center in which Prilosec and Protonix were found to be dangerous following balloon angioplasty. In a five-year follow-up, patients taking Prilosec and Protonix were 72 percent and 54 percent more likely to die, respectively, than patients not on heartburn drugs.
A possible alternative to antacids and acid-reducing drugs are digestive enzyme supplements combined with herbal ingredients, including aloe, DGL and marshmallow, which might help soothe an irritated digestive tract.